Ponthus is a surname. Notable people with the surname include:

Joseph Ponthus (1978–2021), French writer Marc Ponthus, French pianist Sandra Ponthus (born 1976), French diver

See also: Antoine Claude Ponthus-Cinier (1812–1885), French painter

As a given name: Ponthus Westerholm (born 1992), Swedish ice hockey player