Senator Nicholas may refer to:
Members of the United States Senate Robert C. Nicholas (1787–1856), U.S. Senator from Louisiana from 1836 to 1841 Wilson Cary Nicholas (1761–1820), U.S. Senator from Virginia from 1799 to 1804
United States state senate members David R. Nicholas (1941–2005), Wyoming State Senate John Nicholas (congressman) (1764–1819), New York State Senate Phil Nicholas (born 1955), Wyoming State Senate Robert C. Nicholas (New York politician) (1801–1854), New York State Senate
See also Michael San Nicolas (born 1981), Senate of Guam Senator Nichols (disambiguation)