Lopa may refer to:
Layers of protection analysis, a risk management technique Loss-of-pressure-control accident, a mode of failure for a nuclear reactor LoPa, common abbreviation for Finnish football club Lohjan Pallo Layout-Passenger Accommodation, industry term for airline seat Lopa (fly), a genus in family Coelopidae Lopa County, in Imatong State, South Sudan Lopa language, a Kainji language spoken in Nigeria
People Baharuddin Lopa (1935–2001), Indonesian minister and attorney general Dmytro Lopa (born 1988), Ukrainian football midfielder Lopa Patel, British digital entrepreneur