Mailu may refer to:
Mailu Island, in Central Province, Papua New Guinea Mailu language, a Papuan language of Papua New Guinea Mailu (email client), see list of mail server software Maechidius mailu, a species of beetle Cleopa Kilonzo Mailu (born 1956), Kenyan politician Samwel Mailu (born 1993), Kenyan long-distance runner
See also Mailuan languages, a Papuan language family that includes Mailu