Powe is an unincorporated community in southwest Stoddard County, in the U.S. state of Missouri. The community is on Missouri Route U 2.5 miles east of the St. Francis River and two miles north of the Stoddard-Dunklin county line.Missouri Atlas & Gazetteer, DeLorme, 1st ed., 1998, P.67,
History A post office called Powe was established in 1904, and remained in operation until 1929. The community has the name of the Powe family, original owners of the town site.
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