Diadenosine hexaphosphate hydrolase (ATP-forming) (, Ndx1) is an enzyme with systematic name P1,P6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (ATP-forming). This enzyme catalyses the following chemical reaction
(1) P1,P6-bis(5'-adenosyl)hexaphosphate + H2O 2 ATP (2) P1,P5-bis(5'-adenosyl)pentaphosphate + H2O ATP + ADP (3) P1,P4-bis(5'-adenosyl)tetraphosphate + H2O ATP + AMP
The enzyme requires the presence of the divalent cations (Mn2+, Mg2+, Zn2+, and Co2+).
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