Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase (, phnM (gene)) is an enzyme with systematic name alpha-D-ribose-1-methylphosphonate-5-triphosphate diphosphohydrolase. It catalyses the following chemical reaction:
This enzyme characterised from the bacterium Escherichia coli hydrolyses α-D-ribose 1-methylphosphonate 5-triphosphate to remove a pyrophosphate (PPi) group and give α-D-ribose 1-methylphosphonate 5-phosphate. This is part of a pathway that allows microorganisms to metabolise carbon-phosphorus bonds.
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