Detweiler or Dettweiler is a surname of German origin. Notable people with the surname include:
Alan Detweiler (1926–2012), Canadian composer, writer, and patron of the arts Chip Detweiler (1932–1984) American architect Craig Detweiler (born 1964), American writer, filmmaker and cultural commentator Ducky Detweiler (1919–2013), former Major League Baseball player Frederick German Detweiler (1881–1960), American sociologist and expert on race relations Helen Dettweiler (1914–1990), American professional golfer Rene Dettweiler (born 1983), former German boxer
Robert Detweiler (1930–2003), American competition rower, Olympic champion, naval officer, and scientist
Fictional characters Theodore Jasper "T.J." Detweiller, one of the main protagonists in Recess Barry "Dutch" Detweiler, protagonist of Fedora Max Detweiler, character in The Sound of Music based on Franz Wasner
See also Dettwiller in France, Dettweiler Deadwyler Detwiler