5-epiaristolochene 1,3-dihydroxylase (, 5-epi-aristolochene 1,3-dihydroxylase, EAH) is an enzyme with systematic name 5-epiaristolochene,NADPH:oxygen oxidoreductase (1- and 3-hydroxylating). It catalyses the following chemical reaction:
5-epiaristolochene 1,3-dihydroxylase is a cytochrome P450 protein containing heme, isolated from tobacco. It uses molecular oxygen for the oxidation and requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate.
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