TRNA-dihydrouridine20a/20b synthase (NAD(P)+)

TRNA-dihydrouridine20a/20b synthase (NAD(P)+) (, Dus4p) is an enzyme with systematic name tRNA-5,6-dihydrouracil20a/20b:NAD(P)+ oxidoreductase. This enzyme catalyses the following chemical reaction

(1) 5,6-dihydrouracil20a in tRNA + NAD(P)+ uracil20a in tRNA + NAD(P)H + H+ (2) 5,6-dihydrouracil20b in tRNA + NAD(P)+ uracil20b in tRNA + NAD(P)H + H+

A flavoenzyme. The enzyme specifically modifies uracil20a and uracil20b in tRNA.

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