Very-long-chain enoyl-CoA reductase (, TSC13 (gene name), CER10 (gene)) is an enzyme with systematic name very-long-chain acyl-CoA:NADP+ oxidoreductase. This enzyme catalyses the following chemical reaction
a very-long-chain acyl-CoA + NADP+ a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+
This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA.
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