2-dehydro-3-deoxygluconokinase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Escherichia coli converts 2-dehydro-3-deoxy-D-gluconic acid to 2-dehydro-3-deoxy-6-phospho-D-gluconic acid by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP).
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase. Other names in common use include 2-keto-3-deoxygluconokinase, 2-keto-3-deoxy-D-gluconic acid kinase, 2-keto-3-deoxygluconokinase (phosphorylating), 2-keto-3-deoxygluconate kinase, and ketodeoxygluconokinase. It participates in the pentose phosphate pathway.
Structural studies As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .
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