HC, hc or H/C may refer to:
Science, technology, and mathematics Medicine Health Canada Hemicrania continua Hyperelastosis cutis or hereditary equine regional dermal asthenia
Chemistry Hemocyanin, a metalloprotein abbreviated Hc HC smoke, a US military designation for Hexachloroethane Homocapsaicin, a capsaicinoid Hydrocarbon, a category of substances consisting only of hydrogen and carbon
Other uses in science, technology, and mathematics 74HC-series integrated circuits, a logic family of integrated circuits Felix HC, a series of Romanian personal microcomputers produced by ICE Felix Bucharest and which were ZX Spectrum clones Hemianthus callitrichoides, a freshwater aquatic plant native to Cuba + h.c., a notation used in mathematics and quantum physics
Sports Head Coach Hors catégorie (French), used in cycle races to designate a climb that is "beyond categorization" UCI .HC road cycling races (1.HC and 2.HC), the second tier of events in the sport, after the UCI World Tour
Other uses Heritage Corridor, a Metra commuter rail line running from Chicago to Joliet, Illinois Highway contract route, an outsourced United States Postal Service delivery method, formerly known as Star routes Honorary degree, or honoris causa Hors de commerce, prints similar to Artist Proofs except they are only available through the artist directly Hospitality Club, an internet-based hospitality service Houston Chronicle, newspaper of record of Houston, Texas Aero-Tropics Air Services (IATA airline designator HC) Disability, acronym for Handicap/Handicapped High-cube container, a type of intermodal shipping container