DS may refer to:
Arts and entertainment Video games Nintendo DS, handheld game console Nintendo DSi, third iteration of the Nintendo DS Deca Sports, a sports video game series Deca Sports (video game), the first game of the series Double Spoiler, a game in the Touhou Project series Dark Souls, a series of action role-playing games Dark Souls (video game), the first game in the series Death Stranding, an action game Don't Starve, a survival game
Music "D.S." (song), a 1995 song by Michael Jackson Dal segno (D.S.), a navigation marker in music notation
Comics
Demon Slayer: Kimetsu no Yaiba, a Japanese manga series by Koyoharu Gotouge
Organisations Committee for State Security (Bulgaria), a former Bulgarian secret service (Democrats of the Left), a former Italian political party Democratic Party (Demokratska stranka), a political party in Serbia Bureau of Diplomatic Security, in the US Department of State
Science and technology Dwarf spiral galaxy (dS) Darmstadtium (symbol Ds), a chemical element Data science Degree of substitution, relative density of substituent groups in a polymer Dielectric spectroscopy, measuring dielectric properties of medium Directional symmetry (time series) Dnepropetrovsk Sputnik, a class of Soviet satellites
Computing DS register, of X86 processor Avid DS, defunct editing and effects software Delegation Signer, DNSSEC record type DirectShow, Microsoft API Nintendo DS Nintendo DSi DualShock, line of gamepads for PlayStation DeepSeek (chatbot)
Mathematics ds (elliptic function), one of Jacobi's elliptic functions De Sitter space (dS)
Medicine Down syndrome, a genetic disorder Duodenal switch, a weight-loss surgery
Transportation DS Automobiles, a French car marque Citroën DS Inside (2009), a concept car Citroën DS (1955–1975), a car model EasyJet Switzerland (IATA code: DS), an airline
Weapons 7.92 DS, a Polish-designed anti-tank ammunition type DS-39, Degtyaryova Stankovyi Model 1939, a Russian medium machine gun
Other uses Detective Sergeant, UK police rank Detective Superintendent, UK and Australian police rank Diodorus Siculus (D.S. or DS), a first-century BCE Greek historian Dominance and submission (D/s), a set of behaviors Enchiridion symbolorum, definitionum et declarationum de rebus fidei et morum ("Denzinger-Schönmetzer", DS), a book of Catholic dogma Different subject (DS), in switch-reference
See also "DS 21", a 1989 song by Jane Child from Jane Child
D (disambiguation) (for Ds or D's, the plural of "D")