Thomas Bayne may refer to:

Thomas Bayne (Sam Nixon) (1824–1888), American politician and former slave Thomas M. Bayne (1836–1894), American lawyer, politician and American Civil War Union colonel Thomas Vere Bayne (1829–1908), British academic at the University of Oxford T. L. Bayne (Thomas Levingston Bayne Jr.), American football player, coach of football and baseball, and attorney