William Joseph Patrick (Pat) O'Brien (Milwaukee, 11 november 1899 – Santa Monica, 15 oktober 1983) was een Amerikaans acteur van Ierse komaf.
Levensloop O'Brien begon te acteren in 1930. Hij speelde mee in circa 150 films. Hij is vooral bekend voor zijn rollen in de prenten Cowboy from Brooklyn (1938), Knute Rockne, All American (1940) en Some Like It Hot (1959). Hij speelde vaak samen met de acteur James Cagney. O'Brien stierf op 83-jarige leeftijd aan een hartaanval in Santa Monica.
Filmografie 1931: Honor Among Lovers 1931: The Front Page 1931: Personal Maid 1931: Flying High 1931: Consolation Marriage 1932: Hell's House 1932: Scandal for Sale 1932: The Strange Case of Clara Deane 1932: Hollywood Speaks 1932: American Madness 1932: Virtue 1932: Air Mail 1933: Laughter in Hell 1933: Destination Unknown 1933: The World Gone Mad 1933: Bureau of Missing Persons 1933: Flaming Gold 1933: Bombshell 1933: College Coach 1934: I've Got Your Number 1934: Gambling Lady 1934: Twenty Million Sweethearts 1934: Here Comes the Navy 1934: The Personality Kid 1934: Flirtation Walk 1934: I Sell Anything 1935: Devil Dogs of the Air 1935: In Caliente 1935: Oil for the Lamps of China 1935: The Irish in Us 1935: Page Miss Glory 1935: Stars Over Broadway 1936: Ceiling Zero 1936: I Married a Doctor 1936: Public Enemy's Wife 1936: China Clipper 1937: The Great O'Malley 1937: Slim 1937: San Quentin 1937: Back in Circulation 1937: Submarine D-1 1938: Women Are Like That 1938: Panamint's Bad Man 1938: Cowboy from Brooklyn 1938: Boy Meets Girl 1938: Garden of the Moon 1938: Angels with Dirty Faces 1939: Off the Record 1939: The Kid from Kokomo 1939: Indianapolis Speedway 1939: The Night of Nights 1940: Slightly Honorable 1940: The Fighting 69th 1940: Castle on the Hudson 1940: 'Til We Meet Again 1940: Torrid Zone 1940: Escape to Glory 1940: Flowing Gold 1940: Knute Rockne, All American 1941: Doomed Caravan 1941: Bury Me Not on the Lone Prairie 1942: Two Yanks in Trinidad 1942: Broadway 1942: Flight Lieutenant 1942: The Navy Comes Through 1943: Bombardier 1943: The Iron Major 1943: His Butler's Sister 1944: Marine Raiders 1944: Secret Command 1945: Having Wonderful Crime 1945: Man Alive 1946: Perilous Holiday 1946: Crack-Up 1947: Riffraff 1948: Fighting Father Dunne 1948: The Boy with Green Hair 1949: A Dangerous Profession 1950: Johnny One-Eye 1950: The Fireball 1951: Criminal Lawyer 1951: The People Against O'Hara 1952: Okinawa 1954: Jubilee Trail 1954: Ring of Fear 1956: Inside Detroit 1957: Kill Me Tomorrow 1958: The Last Hurrah 1959: Some Like It Hot 1965: Town Tamer 1969: The Over-the-Hill Gang 1970: The Phynx 1975: The Sky's the Limit 1977: Billy Jack Goes to Washington 1978: The End 1981: Ragtime
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Categorie:Amerikaans acteur