William Polk is the name of:
William Polk (colonel) (1758–1834), American Revolutionary War officer, politician and bank president William Benjamin Polk (1930–2014), American state representative William Hawkins Polk (1815–1862), American congressman William J. Polk (c. 1808–1863), American politician William M. Polk (born 1936), American politician William Mecklenburg Polk (1844–1918), American physician William R. Polk (born 1929), foreign policy consultant and author