Big Muddy may refer to:
Places Big Muddy, Wyoming, U.S. Big Muddy Badlands, Saskatchewan, Canada, and Montana, U.S.
Waterways Big Muddy Creek (Missouri River tributary), Saskatchewan, Canada, and Montana, U.S. Big Muddy Creek (East Fork Grand River tributary), a stream in Missouri Big Muddy Creek (Grand River tributary), a stream in Missouri Missouri River, nicknamed "Big Muddy" Mississippi River, nicknamed "The Big Muddy" Big Muddy River, Illinois, U.S. Big Muddy Creek (New Zealand), near the Upper Nihotupu Reservoir Big Muddy Lake, a lake in Saskatchewan
Other uses Big Muddy (film), a 2015 Canadian crime drama Big Muddy National Fish and Wildlife Refuge, along the Missouri River, U.S. Big Muddy oil field, Wyoming, U.S. Big Muddy Records, an independent American music record label Big Muddy River Correctional Center, in Ina, Jefferson County, Illinois Weyburn-Big Muddy, an electoral district in Saskatchewan, Canada "Big Muddy", a song by Bruce Springsteen from the 1992 album Lucky Town
See also "Waist Deep in the Big Muddy", a 1967 anti-war song by Pete Seeger