Siles may refer to:

People Jemma Siles (b. 1997), Australian singer/songwriter Hernando Siles Reyes (b. 1882), 31st President of Bolivia, 27th Vice President of Bolivia Hernán Siles Zuazo (b. 1914), 46th President of Bolivia, 31st Vice President of Bolivia Luis Adolfo Siles Salinas (b. 1925), 49th President of Bolivia Gome de Siles, Spanish noble and knight during the reign of Charles V, Holy Roman Emperor

Places Estadio Hernando Siles, a sports stadium in La Paz, Bolivia Hernando Siles Province, in the Chuquisaca Department, Bolivia Puerto Siles, a town and municipality in Yacuma Province in the Beni Department of northern Bolivia Siles, Jaén, a town in Andalusia, Spain