EFB may refer to:

Science and technology Anisogramma anomala, a plant pathogen affecting Corylus spp. (hazelnut) Electronic flight bag, an information management device for flight crews European foulbrood, a honeybee disease Enhanced flooded battery, an automobile battery technology

Organisations European Federation of Biotechnology French Bilingual School of South Carolina (French: ), US

Sport Esbjerg fB, a Danish football club EfB Ishockey, a Danish professional ice hockey team