Koplowitz is a surname, and may refer to:
Alicia Koplowitz (b. 1954), Spanish businesswoman Dan Koplowitz (b. 1980), founder of US recording label Friendly Fire Recordings Esther Koplowitz (b. 1953), Spanish businesswoman Oskar Koplowitz (1911–1984), German-born US author, known as Oskar Seidlin Zoe Koplowitz (b. 1948), US marathon runner