Knotts is a surname. Notable people with the surname include:
Armanis F. Knotts ( 1860–1937), American politician and lawyer Don Knotts (1924–2006), American comedic actor Gary Knotts (born 1977), American baseball player Howard Knotts, American flying ace during World War I Jake Knotts (born 1944), American politician Ricky Knotts (1951–1980), American ASA and NASCAR driver
See also United States v. Knotts, a 1983 United States Supreme Court case Knott's (disambiguation) Knott (disambiguation)