G80 may refer to:
Technology Nvidia G80, codename for the Nvidia GeForce 8800 series of GPUs Panasonic Lumix DMC-G80, a camera model Sega G80, an arcade board model Transportation
Vehicles BMW G80 M3, a generation of the BMW M3 sports car Genesis G80, a luxury car Innoson IVM G80, an SUV Matchless G80, a motorcycle
Other G80 Guangzhou–Kunming Expressway, an expressway in China Beijing–Hong Kong high-speed train, train service operated by China Railway