Elizabeth Spencer may refer to:
Elizabeth Spencer (writer) (1921–2019), American novelist Elizabeth Spencer (soprano) (1871–1935), American soprano, recording artist for Thomas Alva Edison Lady Elizabeth Spencer (1737–1831), wife of Henry Herbert, 10th Earl of Pembroke Elizabeth Spencer, Baroness Hunsdon (1552–1618), English noblewoman, scholar, and patron of the arts Elizabeth Spencer, Duchess of Marlborough (c. 1713–1761)
Characters Elizabeth Webber, fictional character on the American soap opera General Hospital -- at one time married to Lucky Spencer Betty Spencer, fictional character in Some Mothers Do 'Ave 'Em