Paisano may refer to:
Places in the United States Arizona Casa Juan Paisano, a historic house in Tucson
Texas Paisano Grant, one of twenty-five land grants made in the Brooks County/Jim Wells County area Paisano Park, Texas, a census-designated place in San Patricio County El Paisano Hotel, a historic hotel in Marfa El Paisano Ranch, a ranch in Jim Wells County Edgewater-Paisano, Texas, a suburb of Mathis
Other uses The Paisano, an independent student-run newspaper of the University of Texas at San Antonio Edna Paisano (1948–2014), Nez Perce and Laguna Pueblo demographer and statistician Sphodros paisano, a species of purseweb spider in the family Atypidae Ue... paisano!, a 1953 Argentine film Paisano Productions, producer of Perry Mason (1957 TV series)
See also Paisan, a 1946 Italian neorealist war drama film