Sapiro is one variant of the Ashkenazi Jewish surname Shapiro. Notable people with the surname include:
Aaron Sapiro (1884–1959), American cooperative activist and lawyer Evgeniy Sapiro (1934–2024), Soviet-Russian economist and politician Gisèle Sapiro (born 1965), French sociologist and historian Guillermo Sapiro (born 1966), Uruguayan computer scientist, electrical engineer, and professor Ilya Piatetski-Shapiro (1929–2009), Soviet-born Israeli mathematician Miriam Sapiro (born 1960), American politician Shireen Sapiro (born 1991), South African Paralympic swimmer Virginia Sapiro (born 1951), American political scientist and political psychologist
See also Sapiro, a fictional kingdom in Encantadia, a Filipino fantasy franchise Speyer, a city in Germany
Similar variants of the surname Shapiro: Chapiro Schapira Schapiro Shapero Shapira Spiro Szapiro Szpiro