PNI may refer to:
Organizations Indonesian National Party (Partai Nasional Indonesia), the name used by several political parties in Indonesia Palestinian National Initiative, a Palestinian political party PNI Atlantic News, a Canadian newspaper publisher (formerly SaltWire Network) PNI Digital Media (Photochannel Networks Inc), a US company that operates an on-demand photographic printing service United Nations Crime Prevention and Criminal Justice Programme Network, a global research- and information-sharing network
Science Perineural invasion, cancer spreading along a nerve Psychoneuroimmunology, the study of interaction between the nervous system and immune system
Technology Prescott New Instructions, also known as SSE3, an instruction set introduced with the Intel Prescott processor in 2004 Private Network Interconnect, a method of Internet peering
Other uses PNI, IATA Airport Code for Pohnpei International Airport in Micronesia