Weapon of Choice may refer to:

Weapon of choice, a weapon commonly associated with a certain group or individual

Music Weapon of Choice (band), an American band Weapons of Choice (album), a 2006 album by Treat "Weapon of Choice" (song), a 2000 song by Fatboy Slim "Weapon of Choice", a song by Black Rebel Motorcycle Club from the 2007 album Baby 81

Other uses Weapon of Choice (video game), a 2008 video game Weapons of Choice, a 2004 novel by John Birmingham "Weapon of Choice", a Doctor Who audio play