2V or 2-V may refer to:

2V, IATA code for Amtrak 2V angle, curved isogyre differences in a conoscopic interference pattern in optical crystallography P-2V, a model of Lockheed P-2 Neptune An-2V, a model of Antonov An-2 2V (V-69), manufacturer's designation for Venera 5 spacecraft 2VLY, call sign for Power FM 98.1

See also V2 (disambiguation)