S16 may refer to:
Automobiles Chery QQme, a Chinese city car Peugeot 306 S16, a French family car Proton S16, a Malaysian subcompact car
Aviation Copalis State Airport, in Grays Harbor County, Washington, United States Letov Š-16, a Czechoslovak biplane bomber Rans S-16 Shekari, an American acrobatic monoplane SIAI S.16, an Italian flying boat Sikorsky S-16 a Russian biplane fighter SPAD S.XVI, a French biplane bomber
Rail and transit S16 (ZVV), a rail line of the Zürich S-Bahn Haruka Station, in Ōzu, Ehime Prefecture, Japan Higashi-ojima Station, in Kōtō, Tokyo, Japan Namba Station, in Chūō-ku, Osaka, Japan Seishin-minami Station, in Nishi-ku, Kobe, Japan Shioya Station (Hokkaido), in Otaru, Hokkaido, Japan Tsurusato Station, in Minami-ku, Nagoya, Aichi, Japan
Roads Arlberg Schnellstraße, Austria Expressway S16 (Poland) County Route S16 (California), United States
Vessels
, a submarine of the Royal Navy , a torpedo boat of the Imperial German Navy , a submarine of the United States Navy
Other uses S16 (album), by French musician Woodkid 40S ribosomal protein S16 British NVC community S16, a swamps and tall-herb fens community in the British National Vegetation Classification system S16: Keep away from sources of ignition - No smoking, a safety phrase S16 ribosomal protein leader