Goclenius is a surname. Notable people with the surname include:

Conrad Goclenius (1490-1539), German humanist Rudolph Goclenius (1547–1628), German scholastic philosopher Rudolph Goclenius the Younger (1572–1621), German physician and professor of physics, medicine and mathematics; son of the above Goclenius, a lunar crater named after the younger Goclenius