Benigni is a surname. Notable people with the surname include:
Léon Benigni (1892–1948), French fashion illustrator Mark D. Benigni (born 1972), American politician from Connecticut Roberto Benigni (born 1952), Italian actor, comedian, screenwriter and director Umberto Benigni (1862–1934), Italian Catholic priest and church historian
See also 21662 Benigni (1999 RC), a main-belt asteroid Benign Benigno (disambiguation) Benignus (disambiguation) Benini