Joe or Joseph Spencer may refer to:
Joe Spencer (American football) (1923–1996), American football player Joe Spencer (baseball) (1919–2003), American Negro league baseball player Joseph Spencer (1714–1789), Connecticut lawyer, soldier, and politician Joseph Spencer (New York politician) (1790–1823), New York lawyer and politician Joseph Spencer (cricketer), English cricketer, British Army soldier and inventor Joe Spencer (Hollyoaks), a character in the British soap opera Hollyoaks
Other uses Joseph Spence (disambiguation)