Birtwistle is a surname. Notable people with that surname or similar surnames include:
Adam Birtwistle (born 1959), British artist Alexander Birtwistle (born 1948), retired British Army officer Archibald Cull Birtwistle (1927–2009), retired British Army officer Bill Birtwistle (born 1939), New Zealand rugby union player Deon Birtwistle (born 1980), Australian rower Gordon Birtwistle (born 1943), British Liberal Democrat politician Harrison Birtwistle (1934–2022), British contemporary composer Harry Birtwistle (born 2003), Singaporean footballer Iris Birtwistle (1918–2006), English poet and gallery owner Margaret Birtwistle (1925–1992), British track and field athlete Mark Birtwistle (born 1962), New Zealand rugby union player Silas Birtwistle (born 1963), British artist and sculptor Sue Birtwistle (born 1945), producer and writer of television drama Thomas Birtwistle (1833–1912), English trade unionist and factory inspector
See also Birtwisle, surname Birtwhistle, surname Eva Birthistle (born 1974), Irish actress and writer