Off the Rails may refer to:
Film Off the Rails (1921 film), a German silent drama film Off the Rails (2016 film), an American documentary film about Darius McCollum Off the Rails (2021 film), a British comedy-drama film
Music Off the Rails (song), a 2025 single by Benee Off the Rails, a song by Brantley Gilbert from Tattoos
Television Off the Rails (TV series), an Irish fashion magazine show Off the Rails: A Love Story, a New Zealand railway documentary and travelogue series "Off the Rails" (Star Wars: Young Jedi Adventures), an episode of Star Wars: Young Jedi Adventures
Other uses Off the Rails, a Railway Series book about Gordon the Big Engine Thrillville: Off the Rails, a theme park simulation video game Off the Rails (play), an adaptation of Shakespeare's Measure for Measure from a Native American perspective by Randy Reinholz