VDB or VdB may refer to:

People Alexander Van der Bellen, President of Austria Victor David Brenner, designer of U.S. one-cent coin bearing Abraham Lincoln's image Paul Vanden Boeynants, Belgian prime minister Frank Vandenbroucke (cyclist) Vicente del Bosque, former Spanish footballer and former manager of the Spain national football team Donny van de Beek, Dutch footballer playing for Girona FC

Science and engineering VDB Catalog, list of reflection nebulae compiled by Sidney van den Bergh Video Data Bank, video art distribution service of the Art Institute of Chicago

Computers and technology dBase, abbreviated as VdB , the installed package database in FreeBSD and Gentoo Linux

Other VDB, IATA code for Fagernes Airport, Leirin, Norway Volksdeutsche Bewegung, a former political party in Luxembourg Vrijzinnig Democratische Bond, a Dutch political party Verband der Berufsringer, a defunct German professional wrestling promotion