Klossowski (feminine: Klossowska) is a Polish surname, and may refer to:
Baladine Klossowska Balthazar Klossowski de Rola, the French painter Balthus Erich Klossowski "Madame Klossowski" (Loulou de la Falaise), ex-wife of Thadée Klossowski de Rola, the youngest son of Balthus Pierre Klossowski Setsuko Klossowska de Rola