AHR-1229, also known as N-butyl-N-(1-phenylpyrrolidin-4-yl)tryptamine, is a drug of the tryptamine family which was studied as a possible dopamine antagonist. It increases alertness and produces "small repetitive head movements" in rodents, effects said to be indicative of behavioral excitation, whereas it modestly antagonizes intra-accumbens dopamine-induced hyperlocomotion. Conversely, the drug did not produce catalepsy, did not affect amphetamine-induced lethality, did not affect prolactin levels, and did not displace spiperone binding to dopamine receptors. AHR-1229 was first described in the scientific literature by 1983.
See also Substituted tryptamine
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