Bai Sandra Sinsuat Ampatuan Sema (born June 4, 1966) is a Filipino politician who served as a member of the Philippine House of Representatives for Maguindanao's 1st congressional district from 2010 to 2019. Currently a member of the Bangsamoro Party, she previously served as House deputy speaker from 2016 to 2019.

After her congressional tenure, Sema ran for vice governor of Maguindanao in 2022, but lost to Ainee Sinsuat. She also lost her bids for Maguindanao del Norte's lone district in 2025, and for membership in the Bangsamoro Parliament in 2026.

Sema is the wife of Bangsamoro minister of labor and employment Muslimin Sema.

Electoral history + Electoral history of Bai Sandra Sema Year Office Party Votes received Result Total % . Swing 2001 Vice Governor of ARMM Independent 2,421 0.29% 8th 2010 Representative (Maguindanao–1st) Lakas 143,546 65.98% 1st 2013 rowspan="2" Liberal 1st 2016 1st 2022 Vice Governor of Maguindanao rowspan="2" UBJP 234,591 43.24% 2nd 2025 Representative (Maguindanao del Norte) 117,263 33.38% 2nd 2026 Member of Parliament (Bangsamoro)(Maguindanao del Norte–4th) BaPa 35,603 40.68% 2nd

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