4-Hydroxygramine is a serotonergic drug and a serotonin antagonist belonging to the class of indole-3-methanamines, a family of indoles with a single-carbon chain that are related to tryptamines.
Pharmacology
Pharmacodynamics 4-Hydroxygramine is an antagonist of several subtypes of 5-hydroxytryptamine receptors; it has a high affinity for the 5-HT2C receptor, with an affinity (Ki) of 24 ± 0.8 nM, followed by binding to the 5-HT2A and 5-HT2B receptors (with Ki values of 923 ± 224 and 1242 ± 295, respectively).
See also Gramine
References