Peyrefitte is an Occitan surname. Notable people with this name include:
Roger Peyrefitte (1907–2000), French diplomat and novelist Alain Peyrefitte (1925–1999), French politician and confidante of Charles de Gaulle Michael Peyrefitte, Belizean attorney and politician
Peyrefitte can also refer to:
Peyrefitte-du-Razès, a French commune in the Aude département Peyrefitte-sur-l'Hers, a French commune in the Aude département