Afonso de Noronha (c. 1498–1573) was a Portuguese nobleman, military officer, and governor of Ceuta from 1538 to 1549. He was the fourth son of Fernando de Menezes, 2nd Marquis of Vila Real, and Maria Freire de Andrade. He married Dona Maria de Eça. He succeeded his brother Nuno Álvares Pereira de Noronha, the governor until 1538.
In India, de Noronha served as the 5th Viceroy of India and the Governor of Portuguese India from 1550 to 1554, succeeding governor Jorge Cabral, although some earlier heads of Portuguese India had served only as governors without being appointed Viceroy. In India, he oversaw construction of two fortresses: the Fortaleza dos Reis Magos de Goa and the Fortaleza de Mascate. He pacified Ceylon and defended Hormuz Island when it was attacked by an Ottoman Turkish fleet in 1552. After his term ended, Afonso de Noronha returned to Portugal in January 1555 and was appointed mordomo-mor, or chief steward, to Infanta D. Maria, daughter of D. Manuel I.
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