Sprengel is a surname. Notable people with the surname include:
Hermann Sprengel (1834–1906), chemist Karl or Carl Sprengel (1787–1859), botanist Kurt Sprengel (1766–1833), botanist Christian Konrad Sprengel (1750–1816), teacher and theologist who studied flower biology Bernhard Sprengel (1899–1985), chocolate manufacturer and art collector
See also Sprengel Museum, a museum of modern art in Hanover, Germany Sprengel pump, a vacuum pump invented by Hermann Sprengel