Monadelpha is a genus of flowering plants in the family Euphorbiaceae. It includes a single species, Monadelpha guayanensis, a climbing subshrub native to Amazonas state in southern Venezuela.
The species was first described as Tragia guayanensis by Lynn J. Gillespie in 1994. In 2020 Gillespie and Warren M. Cardinal-McTeague placed the species in the newly-described genus Monadelpha as M. guayanensis.
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