Herff can be both a middle name and a surname. Notable people with the name include:

Given name Marshall Herff Applewhite Jr. (1931–1997), American new religious leader

Surname Ferdinand Ludwig Herff (1820–1912), German-American physician Herbert Herff (1891–1966), American businessman

See also Maximilian von Herff (1893–1945), Nazi German SS commander

Herff–Brooks Corporation, former American automobile manufacturer Herff College of Engineering, in the University of Memphis Herff Jones, American company Herff–Rozelle Farm, historic property in Boerne, Texas, U.S.