The Ministry of Women, Children, Gender and Sexual Minorities and Social Security () is a federal ministry of Nepal established on 13 May 2026, responsible for the protection of marginalised groups and the administration of national social security net.

This ministry was formed by the merger of former Ministry of Women, Children and Senior Citizens with the Social Security wing of Ministry of Labour, Employment and Social Security as part of a broader administrative restructuring by the Balendra Shah-led government under Nepal Government (Work Division) Regulations, 2083.

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