The 1950 Prairie View A&M Panthers football team was an American football team that represented Prairie View A&M College of Texas (now known as Prairie View A&M University) as a member of the Southwestern Athletic Conference (SWAC) during the 1950 college football season. In their second season under head coach James A. Stevens, the Panthers compiled an overall record of 6–4–1, with a mark of 4–3 in conference play, and finished fourth in the SWAC.

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