Will O'Brien may refer to:

Will O'Brien, a character in the 2003–2005 TV series Mile High Will O'Brien, one of the founders of the American fintech company BitGo in 2011 Will O'Brien, one of the interviewees in the 2014 documentary Print the Legend Will O'Brien, an Australian football player in the 2025 Port Adelaide Football Club season Will O'Brien, a character in "A More Perfect Union", a 2016 episode of the TV series Person of Interest

See also

William O'Brien (disambiguation)