The 1933 Langston Lions football team represented Oklahoma Colored Agricultural and Normal University (now known as Langston University) as a member of the Southwestern Athletic Conference (SWAC) during the 1933 college football season. Led by fourth-year head coach Caesar Felton Gayles, the Lions compiled an overall record of 9–1, with a conference record of 4–1, finished as SWAC co-champion, and with a loss against Prairie View in the Prairie View Bowl.
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