The 1933 Prairie View Panthers football team represented Prairie View Normal and Industrial College (now known as Prairie View A&M University) as a member of the Southwestern Athletic Conference (SWAC) during the 1933 college football season. Led by fourth-year head coach Sam B. Taylor, the Panthers compiled an overall record of 7–1, with a conference record of 4–1, finished as SWAC co-champion, and with a victory over Langston in the Prairie View Bowl.

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